ProAnimator comes in two forms: as a standalone application and as an After Effects plug-in. Both products act exactly the same, but the plug-in is integrated into Adobe After Effects, so you can do all of your authoring with After Effects. The standalone application doesn't require a host product, so you may generate your animated movies independent of any particular target. You may even import a standalone ProAnimator scene into the ProAnimator plug-in (or vice versa) for added flexibility.
